CD4 Molecule

《英文msh詞典》CD4 Molecule
[同義詞] CD4 Molecule
[主題詞] Antigens,CD4
[中文釋義] CD4分子
[英文釋義] 55-kD Glycoproteins originally defined as differentiation antigens on T-lymphocytes,but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (Major Histocompatibility Complex) Class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as HIV receptors,binding directly to the envelope protein gp120 on HIV.